Gene

gfm2

ID
ZDB-GENE-060201-3
Name
GTP dependent ribosome recycling factor mitochondrial 2
Symbol
gfm2 Nomenclature History
Previous Names
  • si:dkey-35i22.3 (1)
  • zgc:153835
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Orthologous to human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gfm2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 39 Alliance Combined oxidative phosphorylation deficiency 39 618397
Associated With gfm2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR031157 Tr-type G domain, conserved site
Domain IPR000640 Elongation factor EFG, domain V-like
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR005225 Small GTP-binding protein domain
Domain IPR005517 Translation elongation factor EFG/EF2, domain IV
Domain IPR009022 Elongation factor G, domain III
Domain IPR035649 EFG, domain V
Domain IPR041095 Elongation Factor G, domain II
Family IPR030851 Ribosome-releasing factor 2, mitochondrial
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR035647 EF-G domain III/V-like
Domain Details Per Protein
Protein Length EF-G domain III/V-like EFG, domain V Elongation factor EFG, domain V-like Elongation Factor G, domain II Elongation factor G, domain III P-loop containing nucleoside triphosphate hydrolase Ribosomal protein S5 domain 2-type fold Ribosomal protein S5 domain 2-type fold, subgroup Ribosome-releasing factor 2, mitochondrial Small GTP-binding protein domain Translational (tr)-type GTP-binding domain Translation elongation factor EFG/EF2, domain IV Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily Tr-type G domain, conserved site
UniProtKB:A0JMI9 762
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations