ZFIN ID: ZDB-GENE-060130-5
Gene Name: zinc finger protein, FOG family member 2b
Gene Symbol: zfpm2b    Nomenclature History

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Previous Name: fog2b (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II transcription factor binding activity. Predicted to be involved in cell differentiation; heart development; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in anterior lateral plate mesoderm; central nervous system; midbrain; and posterior lateral plate mesoderm. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).
Genome Resources: Alliance (1),  Gene:568464 (1),  Ensembl(GRCz11):ENSDARG00000100560 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23488 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa30710 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nju206 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-zfpm2b 1
    MO1-zfpm2b N/A 1
    MO2-zfpm2b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zfpm2b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    46,XY sex reversal 9 Alliance 46XY sex reversal 9 616067
    congenital diaphragmatic hernia Alliance Diaphragmatic hernia 3 610187
    tetralogy of Fallot Alliance Tetralogy of Fallot 187500
    DISEASE ASSOCIATED WITH zfpm2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription by RNA polymerase II (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zfpm2b-201 (1)    Ensembl 3684
    zfpm2b-202 (1)    Ensembl 4374
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zfpm2b No data available
    MARKER RELATIONSHIPS
    zfpm2b Contained in: [BAC] CH211-95I5, DKEY-165L8 (order this)
    zfpm2b Encodes: [cDNA] MGC:195117 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001039524 (1) 3684 nt
    Genomic GenBank:BX005062 (1) 170213 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IQP3 (1) 1093 aa
    Sequence Information (all 20)
    ORTHOLOGY for zfpm2b ( Chr: 19 )
    CITATIONS (20)