ZFIN ID: ZDB-GENE-060130-4
Gene Name: zinc finger protein, FOG family member 2a
Gene Symbol: zfpm2a    Nomenclature History

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Previous Names: fog2a (1), zgc:152696

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II transcription factor binding activity. Predicted to be involved in cell differentiation; heart development; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in midbrain. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).
Genome Resources: Alliance (1),  Gene:568996 (1),  Ensembl(GRCz11):ENSDARG00000040123 (2)
GENE EXPRESSION
All Expression Data: Fig. 4 from Walton et al., 2006
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012971Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019806Tg Transgenic Insertion Unknown Unknown DNA
    mn0270Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nju205Gt Transgenic Insertion Unknown Unknown DNA
    sa36240 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42806 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-zfpm2a N/A 1
    MO2-zfpm2a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zfpm2a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    46,XY sex reversal 9 Alliance 46XY sex reversal 9 616067
    congenital diaphragmatic hernia Alliance Diaphragmatic hernia 3 610187
    tetralogy of Fallot Alliance Tetralogy of Fallot 187500
    DISEASE ASSOCIATED WITH zfpm2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription by RNA polymerase II (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zfpm2a-203 (1)    Ensembl 4142
    zfpm2a-204 (1)    Ensembl 402
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zfpm2a No data available
    MARKER RELATIONSHIPS
    zfpm2a Contained in: [BAC] DKEY-64E13 (1) (order this), DKEY-122A22 (1) (order this)
    [PAC] BUSM1-55H21
    zfpm2a Encodes: [cDNA] MGC:152696 (1), MGC:194070 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001039635 (1) 4007 nt
    Genomic GenBank:CR392033 (1) 170291 nt
    Select Tool
    Polypeptide UniProtKB:B2GM62 (1) 1142 aa
    Sequence Information (all 30)
    ORTHOLOGY for zfpm2a ( Chr: 16 )
    CITATIONS (29)