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ZIRC
ZFIN ID: ZDB-GENE-081104-416
Gene Name: mcf.2 cell line derived transforming sequence-like b
Gene Symbol: mcf2lb    Nomenclature History

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Previous Names: sb:eu830, si:dkey-46k9.10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction and regulation of Rho protein signal transduction. Is expressed in lateral line system; otic placode; and otic vesicle. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000076480 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2005 [eu830]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7189 Point Mutation Unknown Premature Stop ENU
sa15537 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41441 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mcf2lb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mcf2lb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mcf2lb-202 (1)    Ensembl 1543
    mcf2lb-203 (1)    Ensembl 1507
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mcf2lb No data available
    MARKER RELATIONSHIPS
    mcf2lb Contained in: [BAC] DKEY-46K9 (1) (order this)
    mcf2lb Encodes: [EST] eu830 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:BX537139 (1) 243063 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7F2V3 (1) 1072 aa
    Sequence Information (all 7)
    ORTHOLOGY for mcf2lb ( Chr: 9 )
    CITATIONS (11)