Gene

masp2

ID
ZDB-GENE-060130-154
Name
MBL associated serine protease 2
Symbol
masp2 Nomenclature History
Previous Names
  • sb:eu714
  • wu:fb62a09
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in complement activation, lectin pathway and proteolysis. Predicted to localize to extracellular space. Is expressed in liver. Orthologous to human MASP2 (mannan binding lectin serine peptidase 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With masp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
MASP2 deficiency 613791
Associated With masp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000742 EGF-like domain
Domain IPR000859 CUB domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR001881 EGF-like calcium-binding domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR037571 Mannan-binding lectin-associated serine peptidase 2
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length CUB domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Mannan-binding lectin-associated serine peptidase 2 Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, serine active site Spermadhesin, CUB domain superfamily Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily
UniProtKB:E9QGP2 376
UniProtKB:E9QCA1 685
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations