ZFIN ID: ZDB-GENE-060126-1
Gene Name: Bardet-Biedl syndrome 1
Gene Symbol: bbs1
Previous Name: im:7144669
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7144669]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa13530 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16994 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: CRISPR1-bbs1 (1), MO1-bbs1 (1), MO2-bbs1 (1), MO3-bbs1 (1), MO4-bbs1 (1)
    PHENOTYPE
    Data: 23 figures from 10 publications
    Observed in: axis, brain, cell migration involved in gastrulation, convergent extension (all 29) expand
    DISEASE ASSOCIATED WITH bbs1 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Bardet-Biedl syndrome Bardet-Biedl syndrome 1 209900
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process Kupffer's vesicle development (more)
    Cellular Component BBSome (more)
    Molecular Function patched binding (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011047 (1)
  • InterPro:IPR027295 (1)
  • InterPro:IPR028784 (1)
  • InterPro:IPR032728 (1)
  • Pfam:PF14779 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA bbs1-001 (1) 2711
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bbs1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    bbs1Contained in: [BAC] DKEY-197A18 (order this), DKEYP-50D11 (1)
    bbs1Encodes: [EST] IMAGE:7144669 (1) (order this)
    [cDNA] MGC:163029 (1) (order this), MGC:193670 (1) (order this), MGC:193678 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001098251 (1) 2781bp
    Genomic GenBank:BX511175 (1) 134295bp
    Select Tool
    Polypeptide UniProtKB:A4QP86 (1) 588aa
    Sequence Clusters UniGene:43752 (1)
    Sequence Information (all 19)
    OTHER bbs1 GENE PAGES 
  • Gene:568986 (1)
  • VEGA:OTTDARG00000028281 (1)
  • Ensembl(GRCz10):ENSDARG00000075169 (1)
  • ORTHOLOGY for bbs1 (Chr: 21) 
    Species Symbol Chromosome Accession # Evidence
    Human BBS1 11
  • Gene:582
  • OMIM:209901
  • HGNC:966
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (28)