ZFIN is now using GRCz12tu for Genomic Data
Gene
lim2.2
- ID
- ZDB-GENE-060124-1
- Name
- lens intrinsic membrane protein 2.2
- Symbol
- lim2.2 Nomenclature History
- Previous Names
-
- mp19-2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in cataract and cataract 19 multiple types. Orthologous to human LIM2 (lens intrinsic membrane protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cataract 19 multiple types | Alliance | Cataract 19, multiple types | 615277 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Lens fibre membrane intrinsic protein | Peripheral myelin protein 22/Epithelial membrane protein-like | PMP-22/EMP/MP20 | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|---|---|
| UniProtKB:Q45RH2 | InterPro | 173 | ||||
| UniProtKB:A0AC58IEZ5 | InterPro | 173 | ||||
| UniProtKB:A0AC58IEZ7 | InterPro | 173 | ||||
| UniProtKB:A0AC58IEZ9 | InterPro | 173 | ||||
| UniProtKB:A0AC58IF07 | InterPro | 173 | ||||
| UniProtKB:A0AC58IF10 | InterPro | 173 | ||||
| UniProtKB:A0AC58IF14 | InterPro | 198 | ||||
| UniProtKB:A0AC58IF18 | InterPro | 173 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lim2.2-201
(1)
|
Ensembl | 619 nt | ||
| ncRNA |
lim2.2-002
(1)
|
Ensembl | 501 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers