ZFIN ID: ZDB-GENE-060118-1
Gene Name: laminin, alpha 1
Gene Symbol: lama1    Nomenclature History

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Previous Names: bal, bashful, zmp:0000000656 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have extracellular matrix structural constituent. Involved in several processes, including camera-type eye development; nervous system development; and notochord cell development. Predicted to localize to basement membrane. Is expressed in several structures, including central nervous system; eye; immature eye; pronephros; and trunk. Orthologous to human LAMA1 (laminin subunit alpha 1).
Genome Resources: Alliance (1),  Gene:569971 (1),  Ensembl(GRCz11):ENSDARG00000102277 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a69 Point Mutation Unknown Missense
b765 Unknown Unknown Unknown
lama1_unspecified Unspecified Unknown Unknown
m102 Unknown Unknown Unknown ENU
m113 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m190 Point Mutation Unknown Premature Stop ENU
    m255 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m268 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m277 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m290 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m296 Unknown Unknown Unknown ENU
    m373 Unknown Unknown Unknown ENU
    m430 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m473 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nt7 Point Mutation Unknown Premature Stop ENU
    rw88 Unknown Unknown Unknown
    sa10397 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13584 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17699 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24576 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37969 Point Mutation Unknown Missense, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44203 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44204 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tb244f Unknown Unknown Unknown ENU
    tc245a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc248f Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf209 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf235 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm220a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm267a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to265 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp82 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp86 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tq210 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tr203 Unknown Unknown Unknown ENU
    tr259 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tt206 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tv36 Unknown Unknown Unknown ENU
    uw1 Point Mutation Unknown Splice Site
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lama1 N/A 4
    MO2-lama1 N/A 5
    MO3-lama1 N/A 1
    MO4-lama1 N/A 1
    MO5-lama1 N/A 4
    MO6-lama1 N/A 1
    DISEASE ASSOCIATED WITH lama1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Poretti-Boltshauser syndrome 615960
    DISEASE ASSOCIATED WITH lama1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel development (more)
    Cellular Component basement membrane (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 31)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lama1-201 (1)    Ensembl 9581
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lama1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    TgBAC(lama1:EGFP) lama1 EGFP Danio rerio 1 1
    TgBAC(lama1:lama1-EGFP) lama1 EGFPlama1 Danio rerio 1 1
    MARKER RELATIONSHIPS
    lama1 Contained in: [BAC] CH73-38N6 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001034986 (1) 9582 nt
    Genomic GenBank:FP101885 (1) 130902 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4II20 (1) 3075 aa
    Sequence Information (all 12)
    ORTHOLOGY for lama1 ( Chr: 24 )
    CITATIONS (72)