Gene
lama1
- ID
- ZDB-GENE-060118-1
- Name
- laminin, alpha 1
- Symbol
- lama1 Nomenclature History
- Previous Names
-
- bal
- bashful
- zmp:0000000656 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including camera-type eye development; nervous system development; and notochord cell development. Predicted to be located in cell junction and extracellular region. Predicted to be part of laminin complex. Predicted to be active in basement membrane. Is expressed in several structures, including central nervous system; eye; immature eye; pronephros; and trunk. Orthologous to human LAMA1 (laminin subunit alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 70 figures from 19 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Poretti-Boltshauser syndrome | 615960 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000034 | Laminin IV |
Domain | IPR000742 | EGF-like domain |
Domain | IPR001791 | Laminin G domain |
Domain | IPR002049 | Laminin-type EGF domain |
Domain | IPR008211 | Laminin, N-terminal |
Domain | IPR009254 | Laminin alpha, domain I |
Domain | IPR010307 | Laminin domain II |
Family | IPR050440 | Laminin/Netrin Extracellular Matrix |
Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
Protein | Additional Resources | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like domain | Laminin alpha, domain I | Laminin domain II | Laminin G domain | Laminin IV | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q45H72 | InterPro | 3075 |
Interactions and Pathways
No data available
Plasmids
No data available