Gene

lama1

ID

ZDB-GENE-060118-1

Name

laminin, alpha 1

Symbol

lama1 Nomenclature History

Previous Names

bal
bashful
zmp:0000000656 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including camera-type eye development; nervous system development; and notochord cell development. Predicted to be located in extracellular region and membrane. Predicted to be active in basement membrane. Is expressed in several structures, including central nervous system; eye; immature eye; pronephros; and trunk. Orthologous to human LAMA1 (laminin subunit alpha 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 12 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 70 figures from 19 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lama1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Poretti-Boltshauser syndrome	615960

Associated With lama1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000034	Laminin IV
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR008211	Laminin, N-terminal
Domain	IPR009254	Laminin alpha, domain I
Domain	IPR010307	Laminin domain II
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily