ZFIN ID: ZDB-GENE-060113-1
Gene Name: ripply transcriptional repressor 1
Gene Symbol: ripply1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Involved in negative regulation of transcription, DNA-templated; regulation of skeletal muscle tissue development; and somitogenesis. Localizes to nucleus. Is expressed in paraxial mesoderm; presumptive paraxial mesoderm; shield; somite; and tail bud. Orthologous to human RIPPLY1 (ripply transcriptional repressor 1).
Genome Resources: Alliance (1),  Gene:654446 (1),  Ensembl(GRCz11):ENSDARG00000054103 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
kt1032 Small Deletion Unknown Unknown TALEN
sdu27 Indel Exon 3 Unknown CRISPR
sud101 Small Deletion Unknown Frameshift TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-ripply1 1
MO1-ripply1 N/A 7
MO2-ripply1 N/A 1
TALEN1-ripply1 1
TALEN2-ripply1 1
DISEASE ASSOCIATED WITH ripply1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ripply1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process somitogenesis (more)
Cellular Component nucleus (more)
Molecular Function protein binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ripply1-202 (1)    Ensembl 1253
ripply1-204 (1)    Ensembl 872
ncRNA ripply1-003 (1)    Ensembl 850
ripply1-004 (1)    Ensembl 823
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ripply1
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(hsp70l:ripply1-MYC) hsp70l MYCripply1 Danio rerio 1 2
Tg(ripply1:GFP) ripply1 GFP Danio rerio 1 1
MARKER RELATIONSHIPS
ripply1 Contained in: [BAC] DKEY-38K9 (1) (order this)
ripply1 Encodes: [cDNA] MGC:194134 (1), MGC:194160 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001039108 (1)
Genomic GenBank:BX530030 (1) 180154 nt
Select Tool
Polypeptide UniProtKB:B3DGI6 (1) 140 aa
Sequence Information (all 18)
ORTHOLOGY for ripply1 ( Chr: 21 )
CITATIONS (39)