Gene

slc8a1b

ID
ZDB-GENE-060110-3
Name
solute carrier family 8 member 1b
Symbol
slc8a1b Nomenclature History
Previous Names
  • ncx1b (1)
  • ncx1n (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have calcium:sodium antiporter activity. Predicted to be involved in calcium ion import across plasma membrane and sodium ion transmembrane transport. Predicted to localize to several cellular components, including axon; postsynapse; and sarcolemma. Is expressed in several structures, including blood; eye; liver; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human SLC8A1 (solute carrier family 8 member A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc8a1b Human Ortholog
No data available
Associated With slc8a1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001623 DnaJ domain
Domain IPR003644 Na-Ca exchanger/integrin-beta4
Domain IPR004837 Sodium/calcium exchanger membrane region
Domain IPR032452 Sodium/calcium exchanger domain, C-terminal extension
Family IPR004836 Sodium/calcium exchanger protein
Homologous_superfamily IPR038081 CalX-like domain superfamily
Domain Details Per Protein
Protein Length CalX-like domain superfamily DnaJ domain Na-Ca exchanger/integrin-beta4 Sodium/calcium exchanger domain, C-terminal extension Sodium/calcium exchanger membrane region Sodium/calcium exchanger protein
UniProtKB:Q32SG7 944
UniProtKB:B3DJB0 942
UniProtKB:B2CZC2 942
UniProtKB:F6PBX0 938
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations