ZFIN ID: ZDB-GENE-051220-1
Gene Name: LIM homeobox 2b
Gene Symbol: lhx2b
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: lhx2, bel, belladonna, zgc:152707

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 7 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  amacrine cell, central nervous system, diencephalon, diencephalon anterior region (all 24) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b700 Small Deletion Exon 3 Frameshift, Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ihb61 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb62 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb63 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • lhx2b_unspecified Unspecified Unknown Unknown
    s385 Unknown Unknown Unknown ENU
    sa6091 Point Mutation Unknown Premature Stop ENU
    sa21179 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tv42z Point Mutation Exon 2 Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-lhx2b (1), MO1-lhx2b, MO2-lhx2b (1), MO3-lhx2b (1)
    PHENOTYPE
    Data: 14 figures from 5 publications
    Observed in: brain ipsilateral region, diencephalon, eye neoplasm, eye (all 18) expand
    DISEASE ASSOCIATED WITH lhx2b HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process thalamus development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001781 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00478 (1)
  • PROSITE:PS50023 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00412 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lhx2b-001 (1) 3677
    lhx2b-002 (1) 869
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lhx2b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lhx2bContained in: [BAC] CH211-146J7 (1) (order this), CH211-159C13 (1) (order this)
    lhx2bEncodes: [cDNA] MGC:152707 (1) (order this), MGC:191665 (1) (order this), MGC:193772 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040010 (1) 3602bp
    Genomic GenBank:BX005074 (1) 153989bp
    Select Tool
    Polypeptide UniProtKB:B0R107 (1) 427aa
    Sequence Clusters UniGene:16318 (1)
    Sequence Information (all 32)
    OTHER lhx2b GENE PAGES
  • Gene:791744 (1)
  • VEGA:OTTDARG00000020556 (1)
  • Ensembl(GRCz10):ENSDARG00000031222 (1)
  • ORTHOLOGY for lhx2b (Chr: 8)
    CITATIONS (50)