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Gene

lhx2b

ID
ZDB-GENE-051220-1
Name
LIM homeobox 2b
Symbol
lhx2b Nomenclature History
Previous Names
  • lhx2
  • bel
  • belladonna
  • zgc:152707
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including camera-type eye development; nervous system development; and optomotor response. Predicted to be active in nucleus. Is expressed in several structures, including brain; forebrain neural keel; forebrain neural rod; optic vesicle; and retina. Used to study congenital nystagmus and pathologic nystagmus. Orthologous to human LHX2 (LIM homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lhx2b Human Ortholog
No data available
Associated With lhx2b Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR001781 Zinc finger, LIM-type
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Zinc finger, LIM-type
UniProtKB:B3DGW8 396
UniProtKB:B0R107 427
UniProtKB:A1L100 396
UniProtKB:F6NJE9 134
UniProtKB:Q1WL64 396
UniProtKB:Q3LHM2 395
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations