Gene

wnt7aa

ID
ZDB-GENE-051129-1
Name
wingless-type MMTV integration site family, member 7Aa
Symbol
wnt7aa Nomenclature History
Previous Names
  • wnt7a
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have cytokine activity and frizzled binding activity. Predicted to be involved in several processes, including canonical Wnt signaling pathway; neuron differentiation; and positive regulation of JNK cascade. Predicted to localize to extracellular space. Is expressed in brain; head; otic vesicle; pectoral fin; and pectoral fin bud. Human ortholog(s) of this gene implicated in Fuhrmann syndrome. Orthologous to human WNT7A (Wnt family member 7A).
Genome Resources
Note
None
Expression
All Expression Data
15 figures from 8 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt7aa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fuhrmann syndrome Alliance Fuhrmann syndrome 228930
Schinzel type phocomelia Alliance Ulna and fibula, absence of, with severe limb deficiency 276820
Associated With wnt7aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Family IPR013300 Wnt-7 protein
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt-7 protein Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:Q4JLT0 349
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations