ZFIN ID: ZDB-GENE-051129-1
Gene Name: wingless-type MMTV integration site family, member 7Aa
Gene Symbol: wnt7aa    Nomenclature History

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Previous Name: wnt7a

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have frizzled binding activity. Predicted to be involved in Wnt signaling pathway; cell fate commitment; and neuron differentiation. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in Fuhrmann syndrome. Is expressed in brain; head; otic vesicle; pectoral fin; and pectoral fin bud. Orthologous to human WNT7A (Wnt family member 7A).
Genome Resources: Alliance (1),  Gene:565714 (1),  Ensembl(GRCz11):ENSDARG00000044827 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH wnt7aa HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fuhrmann syndrome Alliance Fuhrmann syndrome 228930
Ulna and fibula, absence of, with severe limb deficiency 276820
DISEASE ASSOCIATED WITH wnt7aa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process multicellular organism development (more)
Cellular Component extracellular region (more)
Molecular Function signaling receptor binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Family IPR013300 Wnt-7 protein
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA wnt7aa-201 (1)    Ensembl 3435
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM wnt7aa No data available
MARKER RELATIONSHIPS
wnt7aa Contained in: [BAC] DKEY-189A9 (1) (order this)
wnt7aa Encodes: [cDNA] MGC:194676 (1), MGC:194677 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001025540 (1) 1050 nt
Genomic GenBank:CR548622 (1) 137993 nt
Select Tool
Polypeptide UniProtKB:Q4JLT0 (1) 349 aa
Sequence Information (all 15)
ORTHOLOGY for wnt7aa ( Chr: 11 )
CITATIONS (30)