Gene

syn2b

ID
ZDB-GENE-051127-49
Name
synapsin IIb
Symbol
syn2b Nomenclature History
Previous Names
  • zgc:123199
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have ATP binding activity. Predicted to be involved in neurotransmitter secretion. Predicted to localize to synaptic vesicle membrane. Is expressed in DEL; nervous system; spinal cord neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SYN2 (synapsin II).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. S5 from See et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With syn2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
schizophrenia Alliance {Schizophrenia, susceptibility to} 181500
Associated With syn2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019735 Synapsin, conserved site
Domain IPR020897 Synapsin, pre-ATP-grasp domain
Domain IPR020898 Synapsin, ATP-binding domain
Family IPR001359 Synapsin
Family IPR028712 Synapsin-2/3
Homologous_superfamily IPR013815 ATP-grasp fold, subdomain 1
Homologous_superfamily IPR016185 Pre-ATP-grasp domain superfamily
PTM IPR019736 Synapsin, phosphorylation site
Domain Details Per Protein
Protein Length ATP-grasp fold, subdomain 1 Pre-ATP-grasp domain superfamily Synapsin Synapsin-2/3 Synapsin, ATP-binding domain Synapsin, conserved site Synapsin, phosphorylation site Synapsin, pre-ATP-grasp domain
UniProtKB:C5NU62 695
UniProtKB:Q2YDT0 339
UniProtKB:A0A0R4IJU5 695
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations