ZFIN ID: ZDB-GENE-051120-111
Gene Name: GrpE-like 1, mitochondrial
Gene Symbol: grpel1    Nomenclature History

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Previous Name: zgc:123352 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to localize to the PAM complex, Tim23 associated import motor. Orthologous to human GRPEL1 (GrpE like 1, mitochondrial).
Genome Resources: Alliance (1),  Gene:559037 (1),  Ensembl(GRCz11):ENSDARG00000010021 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2354 Point Mutation Unknown Premature Stop ENU
sa21037 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grpel1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grpel1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein folding (more)
    Cellular Component mitochondrion (more)
    Molecular Function adenyl-nucleotide exchange factor activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000740 GrpE nucleotide exchange factor
    Homologous_superfamily IPR009012 GrpE nucleotide exchange factor, head
    Homologous_superfamily IPR013805 GrpE nucleotide exchange factor, coiled-coil
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grpel1-201 (1)    Ensembl 1578
    ncRNA grpel1-002 (1)    Ensembl 705
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grpel1 No data available
    MARKER RELATIONSHIPS
    grpel1 Contained in: [BAC] DKEY-58I8 (1) (order this)
    grpel1 Encodes: [cDNA] MGC:123352 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037384 (1) 1594 bp
    Genomic GenBank:BX908792 (1) 99046 bp
    Select Tool
    Polypeptide UniProtKB:Q32PS5 (1) 217 aa
    Sequence Information (all 9)
    ORTHOLOGY for grpel1 ( Chr: 7 )
    CITATIONS (24)