Gene

numbl

ID
ZDB-GENE-051113-340
Name
NUMB like endocytic adaptor protein
Symbol
numbl Nomenclature History
Previous Names
  • znumb (1)
  • zgc:123031
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Involved in determination of left/right symmetry; negative regulation of Notch signaling pathway; and primitive erythrocyte differentiation. Localizes to cytoplasm. Is expressed in immature eye; integument; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human NUMBL (NUMB like endocytic adaptor protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Bresciani et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With numbl Human Ortholog
No data available
Associated With numbl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006020 PTB/PI domain
Domain IPR010449 NUMB domain
Family IPR016698 Numb/numb-like
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length NUMB domain Numb/numb-like PH-like domain superfamily PTB/PI domain
UniProtKB:Q4U0E8 618
UniProtKB:A0A286Y8T8 640
UniProtKB:A0A2R8QUN0 630
UniProtKB:Q5FBC1 618
UniProtKB:A0A0R4IDU4 618
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations