ZFIN ID: ZDB-GENE-051113-128
Gene Name: myotubularin 1
Gene Symbol: mtm1
Previous Names: fb19c01, im:6903724, wu:fb19c01, zgc:123266
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6903724]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, eye, heart tube, muscle (all 7) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-mtm1 (1), MO2-mtm1 (1), MO3-mtm1 (1), MO4-mtm1 (1)
PHENOTYPE
Data: 20 figures from 5 publications
Observed in: ball, extension, hatching, head (all 26) expand
DISEASE ASSOCIATED WITH mtm1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
centronuclear myopathy Myotubular myopathy, X-linked 310400
GENE ONTOLOGY
Ontology GO Term
Biological Process chordate embryonic development (more)
Cellular Component cellular_component (more)
Molecular Function hydrolase activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000387 (1)
  • InterPro:IPR003595 (1)
  • InterPro:IPR004182 (1)
  • InterPro:IPR010569 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR022587 (1)
  • InterPro:IPR029021 (1)
  • InterPro:IPR030564 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50056 (1)
  • PROSITE:PS51339 (1)
  • Pfam:PF02893 (1)
  • Pfam:PF06602 (1)
  • Pfam:PF12578 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mtm1-001 (1) 3708
    mtm1-002 (1) 771
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mtm1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    mtm1Contained in: [BAC] DKEY-6N21 (1) (order this)
    mtm1Encodes: [EST] fb19c01, IMAGE:6903724 (1) (order this)
    [cDNA] MGC:123266 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037684 (1) 2161bp
    Genomic GenBank:BX005022 (1) 217582bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q32PM3 (1) 639aa
    Sequence Clusters UniGene:76872 (1)
    Sequence Information (all 15)
    OTHER mtm1 GENE PAGES
  • Gene:560881 (1)
  • VEGA:OTTDARG00000035424 (1)
  • Ensembl(GRCz10):ENSDARG00000037560 (1)
  • ORTHOLOGY for mtm1 (Chr: 7)
    Species Symbol Chromosome Accession # Evidence
    Human MTM1 X
  • Gene:4534
  • OMIM:300415
  • HGNC:7448
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Mtm1 X
  • MGI:1099452
  • Gene:17772
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)