ZFIN ID: ZDB-GENE-051113-128
Gene Name: myotubularin 1
Gene Symbol: mtm1
Previous Names: fb19c01, wu:fb19c01, zgc:123266
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, eye, heart tube, muscle (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-mtm1 (1), MO2-mtm1 (1), MO3-mtm1 (1), MO4-mtm1 (1)
PHENOTYPE
Data: 19 figures from 4 publications
Observed in: ball, extension, hatching, head (all 25) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Myotubular myopathy, X-linked 310400
GENE ONTOLOGY
Ontology GO Term
Biological Process chordate embryonic development (more)
Cellular Component cellular_component (more)
Molecular Function hydrolase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000387 (1)
  • InterPro:IPR004182 (1)
  • InterPro:IPR010569 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR029021 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50056 (1)
  • PROSITE:PS51339 (1)
  • Pfam:PF02893 (1)
  • Pfam:PF06602 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mtm1-001 (1) 930
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mtm1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    mtm1 Contained in: [BAC] DKEY-6N21 (1)
    mtm1 Encodes: [EST] fb19c01
    [cDNA] MGC:123266 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037684 (1) 2161 bp
    Genomic GenBank:BX005022 (1) 217582 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q32PM3 (1) 639 aa
    Sequence Clusters UniGene:76872 (1)
    Sequence Information (all 13)
    OTHER mtm1 GENE PAGES
  • Gene:560881 (1)
  • VEGA:OTTDARG00000035424 (1)
  • Ensembl(Zv9):ENSDARG00000037560 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish mtm1 7  
    Human MTM1 X (Xq28)
  • OMIM:300415
  • Gene:4534
  • Mouse Mtm1 X ( 36.55 cM)
  • MGI:1099452
  • Gene:17772
  • Orthology Details
    CITATIONS (17)