Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-051113-128
Gene Name: myotubularin 1
Gene Symbol: mtm1
Previous Names: fb19c01, wu:fb19c01, zgc:123266
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, eye, heart tube, muscle (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-mtm1 (1), MO2-mtm1 (1), MO3-mtm1 (1), MO4-mtm1 (1)
PHENOTYPE
Data: 19 figures from 4 publications
Observed in: ball, extension, hatching, head (all 25) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Myotubular myopathy, X-linked 310400
GENE ONTOLOGY
Ontology GO Term
Biological Process embryo development (more)
Cellular Component cellular_component (more)
Molecular Function hydrolase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000387 (1)
  • InterPro:IPR004182 (1)
  • InterPro:IPR010569 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR029021 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50056 (1)
  • PROSITE:PS51339 (1)
  • Pfam:PF02893 (1)
  • Pfam:PF06602 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mtm1-001 (1) 930
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM mtm1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    mtm1 Contained in: [BAC] DKEY-6N21 (1)
    mtm1 Encodes: [EST] fb19c01
    [cDNA] MGC:123266 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037684 (1) 2161 bp
    Genomic GenBank:BX005022 (1) 217582 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q32PM3 (1) 639 aa
    Sequence Clusters UniGene:76872 (1)
    Sequence Information (all 11)
    OTHER mtm1 GENE PAGES
  • Gene:560881 (1)
  • VEGA:OTTDARG00000035424 (1)
  • Ensembl(Zv9):ENSDARG00000037560 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish mtm1 7  
    Human MTM1 X (Xq28)
  • OMIM:300415
  • Gene:4534
  • Mouse Mtm1 X ( 36.55 cM)
  • MGI:1099452
  • Gene:17772
  • Orthology Details
    CITATIONS (17)