ZFIN ID: ZDB-GENE-051113-128
Gene Name: myotubularin 1
Gene Symbol: mtm1
Sequence Ontology ID : SO:0000704

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Previous Names: fb19c01, im:6903724, wu:fb19c01, zgc:123266

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6903724]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, eye, heart tube, muscle (all 7) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zf711 Small Deletion Exon 5 Frameshift ZINC_FINGER_NUCLEASE
Targeting reagents: MO1-mtm1 (1), MO2-mtm1 (1), MO3-mtm1 (1), MO4-mtm1 (1)
PHENOTYPE
Data: 24 figures from 6 publications
Observed in: ball, extension, hatching, head (all 30) expand
DISEASE ASSOCIATED WITH mtm1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
centronuclear myopathy Myotubular myopathy, X-linked 310400
GENE ONTOLOGY
Ontology GO Term
Biological Process chordate embryonic development (more)
Cellular Component cellular_component (more)
Molecular Function phosphatase activity (more)
GO Terms (all 19)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000387 (1)
  • InterPro:IPR003595 (1)
  • InterPro:IPR004182 (1)
  • InterPro:IPR010569 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR029021 (1)
  • InterPro:IPR030561 (1)
  • InterPro:IPR030564 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50056 (1)
  • PROSITE:PS51339 (1)
  • Pfam:PF02893 (1)
  • Pfam:PF06602 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mtm1-001 (1) 3708
    mtm1-002 (1) 771
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mtm1 No data available
    MARKER RELATIONSHIPS
    mtm1Contained in: [BAC] DKEY-6N21 (1) (order this)
    mtm1Encodes: [EST] fb19c01, IMAGE:6903724 (1) (order this)
    [cDNA] MGC:123266 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037684 (1) 2161bp
    Genomic GenBank:BX005022 (1) 217582bp Blast at MegaBLAST
    Polypeptide UniProtKB:F8W5H1 (1) 639aa
    Sequence Clusters UniGene:76872 (1)
    Sequence Information (all 17)
    OTHER mtm1 GENE PAGES
  • Alliance (1)
  • Gene:560881 (1)
  • VEGA:OTTDARG00000035424 (1)
  • Ensembl(GRCz10):ENSDARG00000037560 (1)
  • ORTHOLOGY for mtm1 (Chr: 7)
    CITATIONS (20)