ZFIN is now using GRCz12tu for Genomic Data
Gene
ago3a
- ID
- ZDB-GENE-051107-16
- Name
- argonaute RISC catalytic component 3a
- Symbol
- ago3a Nomenclature History
- Previous Names
-
- Ago3a (1)
- eif2c3a
- sb:eu275
- sb:eu416
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA endonuclease activity; miRNA binding activity; and single-stranded RNA binding activity. Predicted to be involved in pre-miRNA processing and regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to act upstream of or within regulation of stem cell proliferation; regulation of translation; and regulatory ncRNA-mediated gene silencing. Predicted to be located in P-body. Predicted to be part of RISC complex. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. Is expressed in fin; integument; nervous system; and pleuroperitoneal region. Orthologous to human AGO3 (argonaute RISC catalytic component 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu275 (3 images)
- eu416 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003100 | PAZ domain |
| Domain | IPR003165 | Piwi domain |
| Domain | IPR014811 | Argonaute, linker 1 domain |
| Domain | IPR032472 | Argonaute linker 2 domain |
| Domain | IPR032473 | Protein argonaute, Mid domain |
| Domain | IPR032474 | Protein argonaute, N-terminal |
| Domain | IPR045246 | Argonaute-like, PIWI domain |
| Family | IPR028603 | Protein argonaute-3 |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR036085 | PAZ domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Argonaute-like, PIWI domain | Argonaute, linker 1 domain | Argonaute linker 2 domain | PAZ domain | PAZ domain superfamily | Piwi domain | Protein argonaute-3 | Protein argonaute, Mid domain | Protein argonaute, N-terminal | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q7S8 | InterPro | 860 | |||||||||||
| UniProtKB:A0A8M6YSQ3 | InterPro | 476 | |||||||||||
| UniProtKB:A0A8M3ATW3 | InterPro | 860 | |||||||||||
| UniProtKB:K4I722 | InterPro | 867 | |||||||||||
| UniProtKB:A0AB13A933 | InterPro | 867 | |||||||||||
| UniProtKB:A0AB32T697 | InterPro | 876 | |||||||||||
| UniProtKB:A0AB32T6F6 | InterPro | 875 | |||||||||||
| UniProtKB:A0AB32T7R7 | InterPro | 869 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers