ZFIN ID: ZDB-GENE-051030-97
Gene Name: guanidinoacetate N-methyltransferase
Gene Symbol: gamt
Previous Name: zgc:123136
Location: Chr: 11   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
  brain glial cell, brain neuron, bulbus arteriosus smooth muscle cell, digestive system (all 26) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gamt HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
guanidinoacetate methyltransferase deficiency Cerebral creatine deficiency syndrome 2 612736
GENE ONTOLOGY
Ontology GO Term
Biological Process creatine biosynthetic process (more)
Cellular Component cellular_component (more)
Molecular Function guanidinoacetate N-methyltransferase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR016550 (1)
  • InterPro:IPR026480 (1)
  • InterPro:IPR029063 (1)
  • PROSITE:PS51559 (1)
  • EC:2.1.1.2 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gamt-001 (1) 987
    ncRNA gamt-002 (1) 833
    gamt-003 (1) 378
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gamt No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gamt Contained in: [BAC] CH211-248I1 (1) (order this)
    gamt Encodes: [cDNA] MGC:123136 (1) (order this), MGC:174421 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001105595 (1) 782 bp
    Genomic GenBank:BX279524 (1) 157440 bp
    Select Tool
    Polypeptide UniProtKB:A8E5I0 (1) 234 aa
    Sequence Clusters UniGene:28451 (1)
    Sequence Information (all 17)
    OTHER gamt GENE PAGES
  • Gene:796865 (1)
  • VEGA:OTTDARG00000022427 (1)
  • Ensembl(Zv9):ENSDARG00000070844 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish gamt 11  
    Human GAMT 19 (19p13.3)
  • OMIM:601240
  • Gene:2593
  • Orthology Details
    CITATIONS (19)