ZFIN ID: ZDB-GENE-051030-97
Gene Name: guanidinoacetate N-methyltransferase
Gene Symbol: gamt
Previous Name: zgc:123136
Location: Chr: 11 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
  brain glial cell, brain neuron, bulbus arteriosus smooth muscle cell, digestive system (all 26) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gamt HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
guanidinoacetate methyltransferase deficiency Cerebral creatine deficiency syndrome 2 612736
GENE ONTOLOGY
Ontology GO Term
Biological Process creatine biosynthetic process (more)
Cellular Component cytoplasm (more)
Molecular Function guanidinoacetate N-methyltransferase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR016550 (1)
  • InterPro:IPR026480 (1)
  • InterPro:IPR029063 (1)
  • PROSITE:PS51559 (1)
  • EC:2.1.1.2 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gamt-001 (1) 987
    ncRNA gamt-002 (1) 833
    gamt-003 (1) 378
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gamt No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gamtContained in: [BAC] CH211-248I1 (1) (order this)
    gamtEncodes: [cDNA] MGC:123136 (1) (order this), MGC:174421 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001105595 (1) 782bp
    Genomic GenBank:BX279524 (1) 157440bp
    Select Tool
    Polypeptide UniProtKB:A8E5I0 (1) 234aa
    Sequence Clusters UniGene:28451 (1)
    Sequence Information (all 17)
    OTHER gamt GENE PAGES
  • Gene:796865 (1)
  • VEGA:OTTDARG00000022427 (1)
  • Ensembl(GRCz10):ENSDARG00000070844 (1)
  • ORTHOLOGY for gamt (Chr: 11)
    Species Symbol Chromosome Accession # Evidence
    Human GAMT 19
  • Gene:2593
  • OMIM:601240
  • HGNC:4136
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)