Gene

eif3hb

ID
ZDB-GENE-051030-42
Name
eukaryotic translation initiation factor 3, subunit H, b
Symbol
eif3hb Nomenclature History
Previous Names
  • zgc:123049
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable metallopeptidase activity. Predicted to contribute to translation initiation factor activity. Acts upstream of or within brain development and heart development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic 43S preinitiation complex and eukaryotic translation initiation factor 3 complex. Predicted to be active in polysomal ribosome. Is expressed in brain; esophagus; eye; pericardial region; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in breast cancer; prostate cancer; and prostate carcinoma. Orthologous to human EIF3H (eukaryotic translation initiation factor 3 subunit H).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Choudhuri et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif3hb Human Ortholog
No data available
Associated With eif3hb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000555 JAB1/MPN/MOV34 metalloenzyme domain
Domain IPR037518 MPN domain
Domain IPR045810 eIF3h, C-terminal
Family IPR027524 Eukaryotic translation initiation factor 3 subunit H
Domain Details Per Protein
Protein Length eIF3h, C-terminal Eukaryotic translation initiation factor 3 subunit H JAB1/MPN/MOV34 metalloenzyme domain MPN domain
UniProtKB:Q5PR67 333
UniProtKB:A0A0R4IWM9 77
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations