ZFIN ID: ZDB-GENE-051012-1
Gene Name: B-cell CLL/lymphoma 2a
Gene Symbol: bcl2a
Sequence Ontology ID : SO:0000704

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Previous Names: bcl2, zBlp2 (1)

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 15 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  anterior lateral mesoderm, brain, corpuscles of Stannius, cranial ganglion (all 22) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-bcl2a (1), MO2-bcl2a (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH bcl2a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Leukemia/lymphoma, B-cell, 2
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (more)
Cellular Component integral component of membrane (more)
Molecular Function protein heterodimerization activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002475 (1)
  • InterPro:IPR003093 (1)
  • InterPro:IPR013278 (1)
  • InterPro:IPR013279 (1)
  • InterPro:IPR020717 (1)
  • InterPro:IPR020726 (1)
  • InterPro:IPR026298 (1)
  • PROSITE:PS01080 (1)
  • PROSITE:PS01258 (1)
  • PROSITE:PS50062 (1)
  • PROSITE:PS50063 (1)
  • Pfam:PF00452 (1)
  • Pfam:PF02180 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA bcl2a-001 (1) 1828
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM bcl2a
    Gt(bcl2a-EGFP), Gt2(bcl2a-EGFP), Tg(myo6b:EGFP-bcl2a,myl7:EGFP), Tg(rag2:EGFP-bcl2a), Tg(rag2:mCherry-bcl2a) (all 6) expand
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    bcl2aContained in: [BAC] CH73-74B21 (1) (order this), CH211-121F17 (1) (order this)
    bcl2aEncodes: [cDNA] MGC:162054 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030253 (1) 1150bp
    Genomic GenBank:CU695001 (1) 98270bp
    Select Tool
    Polypeptide UniProtKB:Q564A4 (1) 228aa
    Sequence Clusters UniGene:45607 (1)
    Sequence Information (all 14)
    OTHER bcl2a GENE PAGES
  • Gene:570772 (1)
  • VEGA:OTTDARG00000021372 (1)
  • Ensembl(GRCz10):ENSDARG00000094704 (1)
  • ORTHOLOGY for bcl2a (Chr: 24)
    CITATIONS (112)