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ZIRC
ZFIN ID: ZDB-GENE-051005-2
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Gene Name: NEDD4 E3 ubiquitin protein ligase a
Gene Symbol: nedd4a
Sequence Ontology ID : SO:0001217

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Previous Name: si:ch211-79l17.5

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ubiquitin protein ligase activity. Involved in endothelial to hematopoietic transition and negative regulation of Notch signaling pathway. Predicted to localize to the cytoplasm.  ...
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16624 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22392 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa35609 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Zhang et al., 2015
    Observed in:
    DISEASE ASSOCIATED WITH nedd4a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nedd4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endothelial to hematopoietic transition (more)
    Cellular Component cytoplasm (more)
    Molecular Function transferase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000008 (1)
  • InterPro:IPR000569 (1)
  • InterPro:IPR001202 (1)
  • InterPro:IPR024928 (1)
  • InterPro:IPR035892 (1)
  • InterPro:IPR035983 (1)
  • InterPro:IPR036020 (1)
  • PROSITE:PS01159 (1)
  • PROSITE:PS50004 (1)
  • PROSITE:PS50020 (1)
  • PROSITE:PS50237 (1)
  • Pfam:PF00168 (1)
  • Pfam:PF00397 (1)
  • Pfam:PF00632 (1)
  • EC:2.3.2.26 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nedd4a-201 (1) 7630
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nedd4a No data available
    MARKER RELATIONSHIPS
    nedd4a Contained in: [BAC] CH73-211N20 (1) (order this), CH211-79L17 (1) (order this)
    [Fosmid] CH1073-484L23 (1) (order this)
    nedd4a Has Artifact: [cDNA] MGC:152720 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034186 (1) 2733 bp
    Select Tool
    Genomic GenBank:AL929392 (1) 172427 bp
    Select Tool
    Polypeptide UniProtKB:Q3KRP0 (1) 910 aa
    Select Tool
    Sequence Clusters UniGene:110063 (1)
    Sequence Information (all 13)
    OTHER nedd4a GENE PAGES
  • Alliance (1)
  • Gene:619412 (1)
  • VEGA:OTTDARG00000013802 (1)
  • Ensembl(GRCz11):ENSDARG00000099843 (1)
    • ORTHOLOGY for nedd4a ( Chr: 18 )
    CITATIONS (20)