Gene
nedd4a
- ID
- ZDB-GENE-051005-2
- Name
- NEDD4 E3 ubiquitin protein ligase a
- Symbol
- nedd4a Nomenclature History
- Previous Names
-
- si:ch211-79l17.5
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin protein ligase activity. Involved in endothelial to hematopoietic transition and negative regulation of Notch signaling pathway. Orthologous to human NEDD4 (NEDD4 E3 ubiquitin protein ligase).
- Genome Resources
- Note
- None
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhang et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000008 | C2 domain |
Domain | IPR000569 | HECT domain |
Domain | IPR001202 | WW domain |
Family | IPR024928 | E3 ubiquitin-protein ligase, SMURF1 type |
Homologous_superfamily | IPR035892 | C2 domain superfamily |
Homologous_superfamily | IPR035983 | HECT, E3 ligase catalytic domain |
Homologous_superfamily | IPR036020 | WW domain superfamily |
Domain Details Per Protein
Protein | Length | C2 domain | C2 domain superfamily | E3 ubiquitin-protein ligase, SMURF1 type | HECT domain | HECT, E3 ligase catalytic domain | WW domain | WW domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A0R4IDE6
|
787 | |||||||
UniProtKB:Q3KRP0
|
910 | |||||||
UniProtKB:A0A2R8RJ10
|
361 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
nedd4a-201
(1)
|
7630 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl