ZFIN ID: ZDB-GENE-050920-1
Gene Name: hyaluronan and proteoglycan link protein 1b
Gene Symbol: hapln1b    Nomenclature History

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Previous Names: hapln1, id:ibd5023, wu:fc07e11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have hyaluronic acid binding activity. Involved in sprouting angiogenesis. Predicted to localize to extracellular matrix. Is expressed in blood island; cardiovascular system; hypochord; and mesoderm. Orthologous to human HAPLN1 (hyaluronan and proteoglycan link protein 1).
Genome Resources: Alliance (1),  Gene:569074 (1),  Ensembl(GRCz11):ENSDARG00000068516 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 3 figures (6 images) from Kudoh et al., 2001 [ibd5023]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027196Tg Transgenic Insertion Unknown Unknown DNA
sa5834 Point Mutation Unknown Premature Stop ENU
sa21814 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41738 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hapln1b N/A 1
    DISEASE ASSOCIATED WITH hapln1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hapln1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sprouting angiogenesis (more)
    Cellular Component extracellular matrix (more)
    Molecular Function hyaluronic acid binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hapln1b-201 (1)    Ensembl 4825
    hapln1b-202 (1)    Ensembl 214
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hapln1b No data available
    MARKER RELATIONSHIPS
    hapln1b Contained in: [BAC] CH211-162F9 (1), CH211-171C15 (1)
    hapln1b Encodes: [EST] fc07e11, ibd5023
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_002663658 (1) 1385 nt
    Genomic GenBank:CU459128 (1) 152157 nt
    Select Tool
    Polypeptide UniProtKB:E7FBW8 (1) 353 aa
    Sequence Information (all 23)
    ORTHOLOGY for hapln1b ( Chr: 10 )
    CITATIONS (22)