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ZIRC
ZFIN ID: ZDB-GENE-050913-90
Gene Name: apelin receptor b
Gene Symbol: aplnrb    Nomenclature History

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Previous Names: grn, agtrl1b (1), zgc:114063

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Exhibits apelin receptor activity. Involved in several processes, including circulatory system development; gastrulation; and mesodermal cell migration. Predicted to localize to the plasma membrane. Is expressed in several structures, including angioblastic mesenchymal cell; blastodisc; cardiovascular system; margin; and mesoderm. Orthologous to human APLNR (apelin receptor).
Genome Resources: Alliance (1),  Gene:565492 (1),  Ensembl(GRCz11):ENSDARG00000036670 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a170 Small Deletion Unknown Unknown CRISPR
hu4145 Point Mutation Unknown Unknown
la017638Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mu270 Insertion Exon 1 Premature Stop CRISPR
    s608 Point Mutation Unknown Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-aplnrb 1
    CRISPR2-aplnrb
    2
    CRISPR3-aplnrb 1
    MO1-aplnrb N/A 5
    MO2-aplnrb N/A 2
    MO3-aplnrb N/A 2
    DISEASE ASSOCIATED WITH aplnrb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aplnrb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angioblast cell migration from lateral mesoderm to midline (more)
    Cellular Component plasma membrane (more)
    Molecular Function apelin receptor activity (more)
    GO Terms (all 26)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aplnrb-201 (1)    Ensembl 2087
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aplnrb No data available
    MARKER RELATIONSHIPS
    aplnrb Contained in: [Fosmid] CH1073-111A5 (1) (order this)
    aplnrb Encodes: [cDNA] MGC:114063 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030197 (1) 2147 bp
    Genomic GenBank:CU655827 (1) 39747 bp
    Select Tool
    Polypeptide UniProtKB:A0T2N3 (1) 359 aa
    Sequence Clusters UniGene:88828 (1)
    Sequence Information (all 12)
    ORTHOLOGY for aplnrb ( Chr: 10 )
    CITATIONS (46)