Gene

fbxo6.2

ID
ZDB-GENE-050913-78
Name
F-box protein 6, tandem duplicate 2
Symbol
fbxo6.2 Nomenclature History
Previous Names
  • fbxo44.4
  • zgc:114081
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; glycoprotein catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to SCF ubiquitin ligase complex and cytoplasm. Orthologous to human FBXO44 (F-box protein 44) and FBXO6 (F-box protein 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxo6.2 Human Ortholog
No data available
Associated With fbxo6.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Domain IPR007397 F-box associated (FBA) domain
Family IPR039752 F-box only protein
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR036047 F-box-like domain superfamily
Domain Details Per Protein
Protein Length F-box associated (FBA) domain F-box domain F-box-like domain superfamily F-box only protein Galactose-binding-like domain superfamily
UniProtKB:A0A8M2B992 247
UniProtKB:Q4V8Y9 211
UniProtKB:A0A8M9PKT0 273
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
This gene is in a cluster of ten fbxo6/fbxo44 genes and relationships are difficult to discern. Current analysis (January 2021) suggests three fbxo44 and fbxo6 gene pairs followed by four additional fbxo44 genes.
Citations