Gene
sppl3
- ID
- ZDB-GENE-050913-71
- Name
- signal peptide peptidase 3
- Symbol
- sppl3 Nomenclature History
- Previous Names
-
- fb94d08
- wu:fb94d08
- zgc:114093
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Involved in regulation of neuron apoptotic process. Predicted to localize to Golgi-associated vesicle membrane; integral component of endoplasmic reticulum membrane; and rough endoplasmic reticulum. Is expressed in central nervous system. Orthologous to human SPPL3 (signal peptide peptidase like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1)
- Thisse Expression Data
-
- MGC:114093 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Peptidase A22B, signal peptide peptidase | Presenilin/signal peptide peptidase |
|---|---|---|---|
|
UniProtKB:F1RDS1
|
345 | ||
|
UniProtKB:Q5BP97
|
382 | ||
|
UniProtKB:Q4V8X9
|
345 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available