Gene

grapb

ID
ZDB-GENE-050913-4
Name
GRB2 related adaptor protein b
Symbol
grapb Nomenclature History
Previous Names
  • si:dkeyp-9d4.1
  • zgc:109892
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 114. Orthologous to several human genes including GRAP (GRB2 related adaptor protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Banerjee et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grapb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Deafness, autosomal recessive 114 618456
Associated With grapb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001452 SH3 domain
Family IPR043539 Grb2-like
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Grb2-like SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily
UniProtKB:F1QSQ4 214
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA grapb-201 (1) Havana 3206 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations