ZFIN ID: ZDB-GENE-050913-37
Gene Name: transmembrane protein 106Bb
Gene Symbol: tmem106bb    Nomenclature History

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Previous Name: zgc:114147

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to be involved in dendrite morphogenesis and lysosome localization. Predicted to localize to lysosomal membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM106B (transmembrane protein 106B).
Genome Resources: Alliance (1),  Gene:566699 (1),  Ensembl(GRCz11):ENSDARG00000035949 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020756Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36865 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tmem106bb HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Leukodystrophy, hypomyelinating, 16 617964
    DISEASE ASSOCIATED WITH tmem106bb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dendrite morphogenesis (more)
    Cellular Component lysosomal membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tmem106bb-201 (1)    Ensembl 1189
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tmem106bb No data available
    MARKER RELATIONSHIPS
    tmem106bb Contained in: [BAC] CH211-134N17 (1)
    tmem106bb Encodes: [cDNA] MGC:114147 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045052 (1) 1189 nt
    Genomic GenBank:BX005064 (1) 134157 nt
    Select Tool
    Polypeptide UniProtKB:Q1LWC2 (1) 267 aa
    Sequence Information (all 9)
    ORTHOLOGY for tmem106bb ( Chr: 19 )
    CITATIONS (27)