ZFIN ID: ZDB-GENE-050913-35
Gene Name: protein kinase C and casein kinase substrate in neurons 1b
Gene Symbol: pacsin1b    Nomenclature History

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Previous Names: pacsin1, fe25d06, syndapin I (1), wu:fe25d06, zgc:114042

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have cytoskeletal protein binding activity and phospholipid binding activity. Involved in auditory receptor cell stereocilium organization and cilium assembly. Predicted to localize to cytoskeleton; endosome; and plasma membrane. Is expressed in nervous system; post-vent region; presumptive neural retina; and trunk. Orthologous to human PACSIN1 (protein kinase C and casein kinase substrate in neurons 1).
Genome Resources: Alliance (1),  Gene:619246 (1),  Ensembl(GRCz11):ENSDARG00000042128 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38582 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44647 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-pacsin1b
    1
    CRISPR1-pacsin1b,pacsin2
    1
    CRISPR2-pacsin1b
    1
    MO1-pacsin1b N/A 1
    MO2-pacsin1b N/A 1
    MO3-pacsin1b N/A 1
    DISEASE ASSOCIATED WITH pacsin1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pacsin1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process auditory receptor cell stereocilium organization (more)
    Cellular Component cell junction (more)
    Molecular Function lipid binding (more)
    GO Terms (all 25)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pacsin1b-201 (1)    Ensembl 2622
    pacsin1b-202 (1)    Ensembl 2663
    pacsin1b-203 (1)    Ensembl 561
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pacsin1b No data available
    MARKER RELATIONSHIPS
    pacsin1b Contained in: [BAC] CH211-135I4 (1)
    [Fosmid] CH1073-194M6 (1), CH1073-333H4 (1), ZFOS-1862H6 (1)
    pacsin1b Encodes: [EST] fe25d06
    [cDNA] MGC:114042 (1), MGC:192905 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001033728 (1) 2651 nt
    Genomic GenBank:CU694224 (1) 160982 nt
    Select Tool
    Polypeptide UniProtKB:B2GTA5 (1) 445 aa
    Sequence Information (all 27)
    ORTHOLOGY for pacsin1b ( Chr: 6 )
    CITATIONS (26)