Gene

camk2g1

ID
ZDB-GENE-050913-146
Name
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
Symbol
camk2g1 Nomenclature History
Previous Names
  • camk2ga
  • zgc:109908
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Enables calmodulin-dependent protein kinase activity. Involved in pronephros structural organization. Acts upstream of or within animal organ development and protein autophosphorylation. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including gut; nervous system; neural tube; notochord; and pronephric duct. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
19 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With camk2g1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mental retardation, autosomal dominant 59 618522
Associated With camk2g1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR032710 NTF2-like domain superfamily
Domain Details Per Protein
Protein Length Calcium/calmodulin-dependent protein kinase II, association-domain NTF2-like domain superfamily Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:F1Q7Q1 212
UniProtKB:U3JAY8 327
UniProtKB:Q4V9P8 560
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations