ZFIN ID: ZDB-GENE-050913-144
Gene Name: SMG5 nonsense mediated mRNA decay factor
Gene Symbol: smg5    Nomenclature History

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Previous Name: zgc:113841

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have telomerase RNA binding activity and telomeric DNA binding activity. Involved in chordate embryonic development. Predicted to localize to cytoplasm and telomerase holoenzyme complex. Orthologous to human SMG5 (SMG5 nonsense mediated mRNA decay factor).
Genome Resources: Alliance (1),  Gene:553261 (1),  Ensembl(GRCz11):ENSDARG00000041481 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113841]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16480 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25030 Point Mutation Unknown Premature Stop ENU
    sa42810 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42811 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-smg5 N/A 1
    DISEASE ASSOCIATED WITH smg5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH smg5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component cytoplasm (more)
    Molecular Function telomerase RNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA smg5-201 (1)    Ensembl 3764
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM smg5 No data available
    MARKER RELATIONSHIPS
    smg5 Contained in: [BAC] DKEY-246M23 (1) (order this)
    smg5 Encodes: [cDNA] MGC:113841 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001024923 (1) 3764 nt
    Genomic GenBank:CR848669 (1) 95378 nt
    Select Tool
    Polypeptide UniProtKB:F1R7R1 (1) 1099 aa
    Sequence Information (all 14)
    ORTHOLOGY for smg5 ( Chr: 16 )
    CITATIONS (18)