Gene

macroh2a2

ID
ZDB-GENE-050913-114
Name
macroH2A.2 histone
Symbol
macroh2a2 Nomenclature History
Previous Names
  • H2A2 (1)
  • h2afy2
  • im:6898017
  • wu:fa14g05
  • zgc:114051
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in brain development. Predicted to localize to nucleosome and nucleus. Is expressed in brain; central nervous system; retina; and retinal ganglion cell layer. Orthologous to human MACROH2A2 (macroH2A.2 histone).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Buschbeck et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With macroh2a2 Human Ortholog
No data available
Associated With macroh2a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002589 Macro domain
Domain IPR007125 Histone H2A/H2B/H3
Domain IPR032454 Histone H2A, C-terminal domain
Domain IPR035796 Core histone macro-H2A, macro domain
Family IPR002119 Histone H2A
Family IPR021171 Core histone macro-H2A
Homologous_superfamily IPR009072 Histone-fold
Homologous_superfamily IPR043472 Macro domain-like
Domain Details Per Protein
Protein Length Core histone macro-H2A Core histone macro-H2A, macro domain Histone-fold Histone H2A Histone H2A, C-terminal domain Histone H2A/H2B/H3 Macro domain Macro domain-like
UniProtKB:Q4V914 367
UniProtKB:A0A0R4IAE9 215
UniProtKB:A0A0R4IXR3 81
UniProtKB:A0A0R4IZ93 224
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations