Gene

recql

ID
ZDB-GENE-050809-134
Name
RecQ helicase-like
Symbol
recql Nomenclature History
Previous Names
  • zgc:110631 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have 3'-5' DNA helicase activity; annealing helicase activity; and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Predicted to localize to chromosome; cytoplasm; and nucleus. Is expressed in basal plate midbrain region; central nervous system; and presumptive diencephalon. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and pancreatic cancer. Orthologous to human RECQL (RecQ like helicase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With recql Human Ortholog
No data available
Associated With recql Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001650 Helicase, C-terminal
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR018982 RQC domain
Domain IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain
Family IPR004589 DNA helicase, ATP-dependent, RecQ type
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length ATP-dependent DNA helicase RecQ, zinc-binding domain DEAD/DEAH box helicase domain DNA helicase, ATP-dependent, RecQ type Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RQC domain Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A2R9YJG5 663
UniProtKB:Q1LUY8 639
UniProtKB:Q498Z7 639
UniProtKB:Q5RHI1 639
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations