ZFIN ID: ZDB-GENE-050809-121
Gene Name: P450 (cytochrome) oxidoreductase a
Gene Symbol: pora    Nomenclature History

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Previous Names: por, zgc:110032

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have NADPH-hemoprotein reductase activity; coenzyme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in response to hormone. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in Antley-Bixler syndrome and congenital adrenal hyperplasia. Orthologous to human POR (cytochrome p450 oxidoreductase).
Genome Resources: Alliance (1),  Gene:568202 (1),  Ensembl(GRCz11):ENSDARG00000055092 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu599]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pora HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Antley-Bixler syndrome Alliance Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis 201750
Disordered steroidogenesis due to cytochrome P450 oxidoreductase 613571
DISEASE ASSOCIATED WITH pora VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function FMN binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pora-201 (1)    Ensembl 2993
ncRNA pora-002 (1)    Ensembl 619
pora-003 (1)    Ensembl 547
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pora No data available
MARKER RELATIONSHIPS
pora Contained in: [BAC] DKEY-259J3 (1) (order this)
pora Encodes: [EST] eu599 (1)
[cDNA] MGC:110032 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001034982 (1) 2986 nt
Genomic GenBank:CR925774 (1) 153410 nt
Select Tool
Polypeptide UniProtKB:F1Q7F3 (1) 674 aa
Sequence Information (all 16)
ORTHOLOGY for pora ( Chr: 10 )
CITATIONS (26)