ZFIN ID: ZDB-GENE-050809-12
Gene Name: mitochondrial ribosomal protein L2
Gene Symbol: mrpl2    Nomenclature History

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Previous Name: im:6908224

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to localize to the mitochondrial large ribosomal subunit. Is expressed in visceral fat. Orthologous to human MRPL2 (mitochondrial ribosomal protein L2).
Genome Resources: Alliance (1),  Gene:571648 (1),  Ensembl(GRCz11):ENSDARG00000062568 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6908224]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42316 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42317 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-mrpl2
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mrpl2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mrpl2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process translation (more)
    Cellular Component ribosome (more)
    Molecular Function structural constituent of ribosome (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR002171 Ribosomal protein L2
    Homologous_superfamily IPR008991 Translation protein SH3-like domain superfamily
    Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
    Homologous_superfamily IPR014722 Ribosomal protein L2, domain 2
    Domain IPR022666 Ribosomal Proteins L2, RNA binding domain
    Domain IPR022669 Ribosomal protein L2, C-terminal
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mrpl2 No data available
    MARKER RELATIONSHIPS
    mrpl2 Encodes: [EST] IMAGE:6908224 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001327785 (1)
    Polypeptide UniProtKB:E7F8R3 (1) 294 aa
    Sequence Information (all 11)
    ORTHOLOGY for mrpl2 ( Chr: 13 )
    CITATIONS (17)