ZFIN ID: ZDB-GENE-050809-115
Gene Name: acyl-CoA synthetase long chain family member 1a
Gene Symbol: acsl1a    Nomenclature History

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Previous Names: acsl1, zgc:110081

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have arachidonate-CoA ligase activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty acid metabolic process; lipid biosynthetic process; and long-chain fatty-acyl-CoA biosynthetic process. Predicted to localize to endoplasmic reticulum and membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Orthologous to human ACSL1 (acyl-CoA synthetase long chain family member 1).
Genome Resources: Alliance (1),  Gene:555308 (1),  Ensembl(GRCz11):ENSDARG00000030514 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu853]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011400Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013579Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021010Tg Transgenic Insertion Unknown Unknown DNA
    sa11697 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13904 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19462 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko332a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-acsl1a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acsl1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acsl1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lipid biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acsl1a-201 (1)    Ensembl 4370
    acsl1a-204 (1)    Ensembl 708
    ncRNA acsl1a-002 (1)    Ensembl 559
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acsl1a No data available
    MARKER RELATIONSHIPS
    acsl1a Contained in: [BAC] CH211-197N1 (1), DKEY-228C11 (1) (order this)
    acsl1a Encodes: [EST] eu853 (1), fc74a12 (1)
    [cDNA] MGC:110081 (1), MGC:174617 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001031837 (1) 3248 nt
    Genomic RefSeq:NW_018394470 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A9JT73 (1) 697 aa
    Sequence Information (all 27)
    ORTHOLOGY for acsl1a ( Chr: 1 )
    CITATIONS (33)