ZFIN ID: ZDB-GENE-050809-1
Gene Name: solute carrier family 8 member 1a
Gene Symbol: slc8a1a    Nomenclature History

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Previous Names: ncx1 (1), ncx1a (1), ncx1h (1), tre, tremblor

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Exhibits calcium:sodium antiporter activity. Involved in several processes, including calcium ion transport; cellular calcium ion homeostasis; and sarcomere organization. Predicted to localize to membrane. Is expressed in heart primordium and pericardial region. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human SLC8A1 (solute carrier family 8 member A1).
Genome Resources: Alliance (1),  Gene:553489 (1),  Ensembl(GRCz11):ENSDARG00000013422 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
m116 Unknown Unknown Unknown ENU
m139 Point Mutation Unknown Premature Stop ENU
m158 Unknown Unknown Unknown ENU
m276 Unknown Unknown Unknown ENU
m736 Unknown Unknown Unknown ENU
sa35118 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tc318d Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te381b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-slc8a1a N/A 2
    MO2-slc8a1a N/A 4
    DISEASE ASSOCIATED WITH slc8a1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc8a1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium ion transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium:sodium antiporter activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc8a1a-202 (1)    Ensembl 3647
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc8a1a No data available
    MARKER RELATIONSHIPS
    slc8a1a Contained in: [BAC] DKEY-28O14 (1) (order this), DKEY-218G22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001037102 (1) 2925 nt
    Genomic GenBank:CR556713 (1) 229692 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q32SG8 (1) 974 aa
    Sequence Information (all 31)
    ORTHOLOGY for slc8a1a ( Chr: 11 )
    CITATIONS (48)