ZFIN ID: ZDB-GENE-050808-2
Gene Name: SET domain containing 4
Gene Symbol: setd4    Nomenclature History

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Previous Name: zgc:112252 (1)

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Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine monomethylation and peptidyl-lysine trimethylation. Orthologous to human SETD4 (SET domain containing 4).
Genome Resources: Alliance (1),  Gene:564058 (1),  Ensembl(GRCz11):ENSDARG00000036592 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:112252]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6907442]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021243Tg Transgenic Insertion Unknown Unknown DNA
sa12614 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-setd4 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH setd4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH setd4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peptidyl-lysine monomethylation (more)
    Molecular Function protein-lysine N-methyltransferase activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001214 SET domain
    Domain IPR015353 Rubisco LSMT, substrate-binding domain
    Family IPR016852 SET domain methyltransferase
    Homologous_superfamily IPR036464 Rubisco LSMT, substrate-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA setd4-201 (1)    Ensembl 1987
    setd4-202 (1)    Ensembl 789
    ncRNA setd4-003 (1) 721
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM setd4 No data available
    MARKER RELATIONSHIPS
    setd4 Contained in: [BAC] CH211-287J19 (1)
    setd4 Encodes: [EST] IMAGE:6907442 (1)
    [cDNA] MGC:112252 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045562 (1) 1846 bp
    Genomic GenBank:BX005416 (1) 163197 bp
    Select Tool
    Polypeptide UniProtKB:A8E7F0 (1) 440 aa
    Sequence Information (all 13)
    ORTHOLOGY for setd4 ( Chr: 1 )
    CITATIONS (23)