ZFIN ID: ZDB-GENE-050720-2
Gene Name: dihydropyrimidinase like 3
Gene Symbol: dpysl3    Nomenclature History

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Previous Name: CRMP-4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in axon guidance and peripheral nervous system neuron axonogenesis. Predicted to localize to cytosol. Is expressed in nervous system; neural plate; spinal cord neural tube; and trigeminal placode. Orthologous to human DPYSL3 (dihydropyrimidinase like 3).
Genome Resources: Alliance (1),  Gene:553166 (1),  Ensembl(GRCz11):ENSDARG00000002587 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022039Tg Transgenic Insertion Unknown Unknown DNA
sa37377 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dpysl3 N/A 4
    MO2-dpysl3 N/A 1
    DISEASE ASSOCIATED WITH dpysl3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dpysl3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon guidance (more)
    Cellular Component cell projection (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dpysl3-201 (1)    Ensembl 5023
    dpysl3-202 (1)    Ensembl 689
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dpysl3 No data available
    MARKER RELATIONSHIPS
    dpysl3 Contained in: [BAC] CH73-280B7 (1)
    dpysl3 Encodes: [cDNA] MGC:193829 (1), MGC:193863 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020512 (1) 5026 nt
    Genomic GenBank:CU462980 (1) 116857 nt
    Select Tool
    Polypeptide UniProtKB:Q52PJ5 (1) 567 aa
    Sequence Information (all 15)
    ORTHOLOGY for dpysl3 ( Chr: 21 )
    CITATIONS (35)