ZFIN ID: ZDB-GENE-050706-167
Gene Name: N-terminal EF-hand calcium binding protein 2
Gene Symbol: necab2    Nomenclature History

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Previous Names: im:6912315, zgc:112232 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Predicted to be involved in regulation of amyloid precursor protein biosynthetic process. Predicted to localize to cytoplasm. Is expressed in brain; central nervous system; cranial ganglion; and neurons. Orthologous to human NECAB2 (N-terminal EF-hand calcium binding protein 2).
Genome Resources: Alliance (1),  Gene:565258 (1),  Ensembl(GRCz11):ENSDARG00000056745 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 4 figures (7 images) from Thisse et al., 2004 [IMAGE:6912315]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020324Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027927Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13964 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36646 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH necab2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH necab2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of amyloid precursor protein biosynthetic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA necab2-201 (1)    Ensembl 4285
    ncRNA necab2-002 (1)    Ensembl 702
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM necab2 No data available
    MARKER RELATIONSHIPS
    necab2 Contained in: [BAC] CH73-22B10 (1), CH211-267G5 (1)
    necab2 Encodes: [EST] IMAGE:6912315 (1)
    [cDNA] MGC:112232 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030195 (1) 1031 nt
    Genomic GenBank:BX908396 (1) 149493 nt
    Select Tool
    Polypeptide UniProtKB:A3KQL1 (1) 428 aa
    Sequence Information (all 15)
    ORTHOLOGY for necab2 ( Chr: 18 )
    CITATIONS (25)