ZFIN ID: ZDB-GENE-050706-140
Gene Name: exosome component 3
Gene Symbol: exosc3
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: im:7140537, zgc:112345 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have RNA binding activity; involved in axonogenesis, cerebellar Purkinje cell layer structural organization, and chordate embryonic development; predicted to localize to the cytoplasmic  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7140537]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fcc363p1Gt Transgenic Insertion Unknown Splicing Variant DNA
la027577Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 4 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH exosc3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    pontocerebellar hypoplasia type 1B Pontocerebellar hypoplasia, type 1B 614678
    DISEASE ASSOCIATED WITH exosc3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component exosome (RNase complex) (more)
    Molecular Function RNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004088 (1)
  • InterPro:IPR012340 (1)
  • InterPro:IPR026699 (1)
  • InterPro:IPR036612 (1)
  • InterPro:IPR037319 (1)
  • Pfam:PF15985 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA exosc3-001 (1) 988
    ncRNA exosc3-002 (1) 810
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM exosc3 No data available
    MARKER RELATIONSHIPS
    exosc3Contained in: [BAC] CH211-273E20 (1) (order this)
    exosc3Encodes: [EST] IMAGE:7140537 (1) (order this)
    [cDNA] MGC:112345 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001029961 (1) 950bp
    Genomic GenBank:AL954718 (1) 163689bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IRK6 (1) 247aa
    Sequence Clusters UniGene:150986 (1)
    Sequence Information (all 10)
    OTHER exosc3 GENE PAGES
  • Alliance (1)
  • Gene:565000 (1)
  • VEGA:OTTDARG00000028192 (1)
  • ORTHOLOGY for exosc3 (Chr: 14)
    CITATIONS (22)