ZFIN ID: ZDB-GENE-050626-97
Gene Name: troponin T2d, cardiac
Gene Symbol: tnnt2d    Nomenclature History

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Previous Name: zgc:114184

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Involved in sarcomere organization. Predicted to localize to the troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Is expressed in myotome and somite. Orthologous to human TNNT2 (troponin T2, cardiac type).
Genome Resources: Alliance (1),  Gene:574000 (1),  Ensembl(GRCz11):ENSDARG00000002988 (1)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2005 [eu989]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023207Tg Transgenic Insertion Unknown Unknown DNA
la023208Tg Transgenic Insertion Unknown Unknown DNA
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-tnnt2d N/A 1
PHENOTYPE
Data: Fig. 8 from Ferrante et al., 2011
Observed in:
DISEASE ASSOCIATED WITH tnnt2d HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tnnt2d VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sarcomere organization (more)
Cellular Component troponin complex (more)
Molecular Function CONTRIBUTES_TO   calcium-dependent ATPase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR001978 Troponin
Family IPR027707 Troponin T
Homologous_superfamily IPR038077 Troponin domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA tnnt2d-202 (1)    Ensembl 968
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tnnt2d No data available
MARKER RELATIONSHIPS
tnnt2d Contained in: [BAC] DKEY-206M15 (1) (order this)
tnnt2d Encodes: [EST] eu989 (1)
[cDNA] MGC:114184 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001025179 (1) 981 nt
Genomic GenBank:BX928758 (1) 199974 nt
Select Tool
Polypeptide UniProtKB:F1QBR1 (1) 241 aa
Sequence Information (all 11)
ORTHOLOGY for tnnt2d ( Chr: 25 )
CITATIONS (24)