ZFIN ID: ZDB-GENE-050626-55
Gene Name: cathepsin S, ortholog 2, tandem duplicate 2
Gene Symbol: ctss2.2    Nomenclature History

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Previous Names: ctssb.2 (1), ctssb2 (1), wu:fj84d06, zgc:111950, zgc:112489

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in immune response and proteolysis involved in cellular protein catabolic process. Predicted to localize to extracellular space and lysosome. Is expressed in blood; macrophage; and yolk syncytial layer. Human ortholog(s) of this gene implicated in neuropathy. Orthologous to human CTSS (cathepsin S).
Genome Resources: Alliance (1),  Gene:337572 (1),  Ensembl(GRCz11):ENSDARG00000013771 (2)
GENE EXPRESSION
All Expression Data: 14 figures from 2 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [MGC:112489]
  6 figures (8 images) from Thisse et al., 2004 [MGC:111950]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ctss2.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ctss2.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component extracellular space (more)
Molecular Function cysteine-type peptidase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ctss2.2-201 (1)    Ensembl 1267
ncRNA ctss2.2-002 (1)    Ensembl 615
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ctss2.2 No data available
MARKER RELATIONSHIPS
ctss2.2 Contained in: [BAC] DKEY-30O16 (1) (order this)
ctss2.2 Encodes: [EST] fj84d06 (1)
[cDNA] MGC:111950 (1), MGC:112489 (1), MGC:191537 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001017661 (1) 1238 nt
Genomic GenBank:BX248517 (1) 201353 nt Blast at MegaBLAST
Polypeptide UniProtKB:A2BF64 (1) 330 aa
Sequence Information (all 21)
ORTHOLOGY for ctss2.2 ( Chr: 16 )
CITATIONS (27)