ZFIN ID: ZDB-GENE-050626-112
Gene Name: myosin, light chain 4, alkali; atrial, embryonic
Gene Symbol: myl4    Nomenclature History

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Previous Names: im:7136900, zgc:114164

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Is expressed in cephalic musculature; myotome; pectoral fin musculature; and somite. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human MYL4 (myosin light chain 4).
Genome Resources: Alliance (1),  Gene:574004 (1),  Ensembl(GRCz11):ENSDARG00000011519 (1)
GENE EXPRESSION
All Expression Data: 7 figures from 3 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2004 [IMAGE:7136900]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH myl4 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Atrial fibrillation, familial, 18 617280
DISEASE ASSOCIATED WITH myl4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component cellular_component (more)
Molecular Function calcium ion binding (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myl4-201    Ensembl 1199
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myl4
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(myh6:myl4,cryaa:mCherry) cryaamyh6 mCherrymyl4 Danio rerio 1 1
Tg(myh6:myl4_E17K,cryaa:mCherry) cryaamyh6 mCherrymyl4 Danio rerio 1 1
MARKER RELATIONSHIPS
myl4 Contained in: [BAC] CH73-176F10 (1)
myl4 Encodes: [EST] IMAGE:7136900 (1)
[cDNA] MGC:114164 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001025183 (1) 1221 nt
Genomic GenBank:CU467632 (1) 54849 nt
Select Tool
Polypeptide UniProtKB:F1Q6V0 (1) 187 aa
Sequence Information (all 11)
ORTHOLOGY for myl4 ( Chr: 3 )
CITATIONS (20)