header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050624-1
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: angiopoietin-like 2b
Gene Symbol: angptl2b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: angptl2, wu:fc41g02

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Involved in angiogenesis; hemopoiesis; and positive regulation of Notch signaling pathway. Is expressed in several structures, including fin; gill; liver; spleen; and yolk. Orthologous to human ANGPTL2 (angiopoietin like 2).
Genome Resources: Alliance (1),  Gene:503514 (1),  Ensembl(GRCz11):ENSDARG00000068369 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029474Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa9722 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa34443 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-angptl2b N/A 2
    MO2-angptl2b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH angptl2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH angptl2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002181 (1)
  • InterPro:IPR020837 (1)
  • InterPro:IPR036056 (1)
  • PROSITE:PS00514 (1)
  • PROSITE:PS51406 (1)
  • Pfam:PF00147 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA angptl2b-201 (1)    Ensembl 3472
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM angptl2b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:angptl2b) hsp70l angptl2b Danio rerio 1 2
    MARKER RELATIONSHIPS
    angptl2b Contained in: [BAC] CH211-281H24 (1) (order this)
    angptl2b Encodes: [EST] fc41g02
    [cDNA] MGC:194321 (1) (order this), MGC:194334 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001126478 (1) 3472 bp
    Select Tool
    Genomic GenBank:CR361562 (1) 160720 bp
    Select Tool
    Polypeptide UniProtKB:B0UXH5 (1) 519 aa
    Select Tool
    Sequence Clusters UniGene:1725 (1)
    Sequence Information (all 25)
    ORTHOLOGY for angptl2b ( Chr: 8 )
    CITATIONS (23)