ZFIN ID: ZDB-GENE-050616-11
Gene Name: gap junction protein, alpha 5b
Gene Symbol: gja5b
Sequence Ontology ID : SO:0000704

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Previous Names: cx41.8, leo, leopard, tup (1)

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
  brain, caudal fin, eye, fin (all 8) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dt3oj022 Point Mutation Unknown Unknown ENU
dtk3 Point Mutation Unknown Unknown ENU
dtnr16 Point Mutation Unknown Unknown ENU
dtnz Point Mutation Unknown Unknown ENU
dtq270 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • dtw28 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • gja5b_unspecified Unspecified Unknown Unknown
    sa19565 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19566 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • t1 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • to29 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 22 figures from 9 publications
    Observed in: adult behavior, anal fin melanocyte, anal fin melanophore stripe, anal fin (all 18) expand
    DISEASE ASSOCIATED WITH gja5b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial atrial fibrillation Atrial fibrillation, familial, 11 614049
    Atrial standstill, digenic (GJA5/SCN5A) 108770
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pigmentation (more)
    Cellular Component cell junction (more)
    Molecular Function gap junction hemi-channel activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000500 (1)
  • InterPro:IPR002264 (1)
  • InterPro:IPR013092 (1)
  • InterPro:IPR017990 (1)
  • InterPro:IPR019570 (1)
  • InterPro:IPR031862 (1)
  • InterPro:IPR034634 (1)
  • PROSITE:PS00407 (1)
  • PROSITE:PS00408 (1)
  • Pfam:PF00029 (1)
  • Pfam:PF16791 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cx41.8-001 (1) 2801
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gja5b
    Tg(cx41.8:cx41.8), Tg(cx41.8:cx45.6), Tg(cx41.8:EGFP), Tg(mitfa:cx41.8), Tg(mitfa:gja5b_I203F) (all 9) expand
    MARKER RELATIONSHIPS
    gja5bContained in: [BAC] CH73-191D11 (1) (order this)
    [Fosmid] CH1073-229O2 (1) (order this)
    gja5bEncodes: [cDNA] MGC:194821 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034988 (1) 2825bp
    Genomic GenBank:CU896648 (1) 67673bp
    Select Tool
    Polypeptide UniProtKB:B3DID2 (1) 370aa
    Sequence Clusters UniGene:135739 (1)
    Sequence Information (all 15)
    OTHER gja5b GENE PAGES
  • Alliance (1)
  • Gene:570445 (1)
  • VEGA:OTTDARG00000035178 (1)
  • Ensembl(GRCz10):ENSDARG00000069450 (1)
  • ORTHOLOGY for gja5b (Chr: 1)
    CITATIONS (69)