ZFIN ID: ZDB-GENE-050525-3
Gene Name: interleukin 12Ba
Gene Symbol: il12ba
Previous Names: il-12p40.a (1), il12b, zgc:152789
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
  dendritic cell, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa18013 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH il12ba HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Immunodeficiency 29, mycobacteriosis 614890
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process positive regulation of NK T cell activation (more)
    Cellular Component extracellular space (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR015528 (1)
  • InterPro:IPR019482 (1)
  • Pfam:PF10420 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA il12ba-001 (1) 1343
    il12ba-002 (1) 1107
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM il12ba No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    il12baContained in: [BAC] CH73-197E12 (1) (order this), CH73-242A13 (1) (order this), CH211-128A7 (order this), DKEYP-22F6
    il12baEncodes: [cDNA] MGC:152789 (1) (order this), MGC:191752 (1)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007108 (1) 1343bp
    Genomic GenBank:BX005211 191332bp
    Select Tool
    Polypeptide UniProtKB:A8WH99 (1) 350aa
    Sequence Clusters UniGene:135198 (1)
    Sequence Information (all 23)
    OTHER il12ba GENE PAGES 
  • Gene:445373 (1)
  • VEGA:OTTDARG00000028013 (1)
  • Ensembl(GRCz10):ENSDARG00000033727 (1)
  • ORTHOLOGY for il12ba (Chr: 14) 
    Species Symbol Chromosome Accession # Evidence
    Human IL12B 5
  • Gene:3593
  • OMIM:161561
  • HGNC:5970
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Il12b 11
  • MGI:96540
  • Gene:16160
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (22)