ZFIN ID: ZDB-GENE-050525-3
Gene Name: interleukin 12Ba
Gene Symbol: il12ba
Previous Names: il-12p40.a (1), il12b, zgc:152789
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
  dendritic cell, whole organism
MUTANTS AND TARGETED KNOCKDOWNS

Allele Type Mutagen Suppliers
sa18013 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Phenotype of Human Orthologue OMIM Phenotype ID
    Immunodeficiency 29, mycobacteriosis 614890
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biological_process (more)
    Cellular Component extracellular space (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR015528 (1)
  • InterPro:IPR019482 (1)
  • Pfam:PF10420 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA il12ba-001 (1) 1343
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM il12ba No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    il12ba Contained in: [BAC] CH73-197E12 (1) (order this), CH73-242A13 (1) (order this), CH211-128A7 (order this), DKEYP-22F6
    il12ba Encodes: [cDNA] MGC:152789 (1) (order this), MGC:191752 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007108 (1) 1343 bp
    Genomic GenBank:BX005211 191332 bp
    Select Tool
    Polypeptide UniProtKB:A8WH99 (1) 350 aa
    Sequence Clusters UniGene:135198 (1)
    Sequence Information (all 23)
    OTHER il12ba GENE PAGES
  • Gene:445373 (1)
  • VEGA:OTTDARG00000028013 (1)
  • Ensembl(Zv9):ENSDARG00000033727 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish il12ba 14  
    Human IL12B 5 (5q31.1-q33.1)
  • OMIM:161561
  • Gene:3593
  • Mouse Il12b 11 ( 25.94 cM)
  • MGI:96540
  • Gene:16160
  • Orthology Details
    CITATIONS (21)