ZFIN ID: ZDB-GENE-050525-3
Gene Name: interleukin 12Ba
Gene Symbol: il12ba
Previous Names: il-12p40.a (1), il12b, zgc:152789
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
  dendritic cell, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa18013 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH il12ba HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Immunodeficiency 29, mycobacteriosis 614890
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of NK T cell activation (more)
    Cellular Component extracellular space (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR015528 (1)
  • InterPro:IPR019482 (1)
  • Pfam:PF10420 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA il12ba-001 (1) 1343
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM il12ba No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    il12ba Contained in: [BAC] CH73-197E12 (1) (order this), CH73-242A13 (1) (order this), CH211-128A7 (order this), DKEYP-22F6
    il12ba Encodes: [cDNA] MGC:152789 (1) (order this), MGC:191752 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007108 (1) 1343 bp
    Genomic GenBank:BX005211 191332 bp
    Select Tool
    Polypeptide UniProtKB:A8WH99 (1) 350 aa
    Sequence Clusters UniGene:135198 (1)
    Sequence Information (all 23)
    OTHER il12ba GENE PAGES
  • Gene:445373 (1)
  • VEGA:OTTDARG00000028013 (1)
  • Ensembl(Zv9):ENSDARG00000033727 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish il12ba 14  
    Human IL12B 5 (5q33.3)
  • OMIM:161561
  • Gene:3593
  • Mouse Il12b 11 ( 25.94 cM)
  • MGI:96540
  • Gene:16160
  • Orthology Details
    CITATIONS (21)