Gene

hs6st1a

ID
ZDB-GENE-050524-1
Name
heparan sulfate 6-O-sulfotransferase 1a
Symbol
hs6st1a Nomenclature History
Previous Names
  • 6-ost-1a (1)
  • hs6st1 (1)
  • zgc:110038
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits heparan sulfate 6-O-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to localize to integral component of membrane. Is expressed in several structures, including immature eye; nervous system; neural keel; neural tube; and polster. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hs6st1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 15 with or without anosmia Alliance {Hypogonadotropic hypogonadism 15 with or without anosmia} 614880
Associated With hs6st1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005331 Sulfotransferase
Family IPR010635 Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase P-loop containing nucleoside triphosphate hydrolase Sulfotransferase
UniProtKB:B2GPW0 405
UniProtKB:Q56UJ5 413
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations