Gene

derl2

ID
ZDB-GENE-050522-90
Name
derlin 2
Symbol
derl2 Nomenclature History
Previous Names
  • zgc:110436
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have misfolded protein binding activity and ubiquitin-specific protease binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and ubiquitin-dependent ERAD pathway. Predicted to localize to Hrd1p ubiquitin ligase ERAD-L complex and integral component of endoplasmic reticulum membrane. Orthologous to human DERL2 (derlin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With derl2 Human Ortholog
No data available
Associated With derl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR007599 Derlin
Homologous_superfamily IPR035952 Rhomboid-like superfamily
Domain Details Per Protein
Protein Length Derlin Rhomboid-like superfamily
UniProtKB:Q4VBS8 239
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA derl2-201 (1) Ensembl 4,971 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations