ZFIN ID: ZDB-GENE-050522-84
Gene Name: calpain 2, (m/II) large subunit b
Gene Symbol: capn2b    Nomenclature History

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Previous Names: im:6908877, zgc:109906

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Is expressed in several structures, including digestive system; germ ring; hatching gland; periderm; and polster. Orthologous to human CAPN2 (calpain 2).
Genome Resources: Alliance (1),  Gene:563053 (1),  Ensembl(GRCz11):ENSDARG00000055592 (2)
GENE EXPRESSION
All Expression Data: 17 figures from 4 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [MGC:109906]
  6 figures (7 images) from Thisse et al., 2004 [IMAGE:6908877]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011709Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9474 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19299 Point Mutation Unknown Premature Stop ENU
    sa24190 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37530 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH capn2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH capn2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component cytoplasm (more)
    Molecular Function calcium-dependent cysteine-type endopeptidase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA capn2b-201 (1)    Ensembl 2454
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM capn2b No data available
    MARKER RELATIONSHIPS
    capn2b Contained in: [BAC] CH211-203K12 (1), DKEYP-101G1 (1)
    capn2b Encodes: [EST] IMAGE:6908877 (1)
    [cDNA] MGC:109906 (1), MGC:174280 (1), MGC:192735 (1), MGC:198150 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001018227 (1) 2481 nt
    Genomic GenBank:BX004801 113290 nt
    Select Tool
    Polypeptide UniProtKB:A5PMP0 (1) 696 aa
    Sequence Information (all 28)
    ORTHOLOGY for capn2b ( Chr: 22 )
    CITATIONS (29)