ZFIN ID: ZDB-GENE-050522-65
Gene Name: nitrilase family, member 2
Gene Symbol: nit2    Nomenclature History

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Previous Name: zgc:109720 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have omega-amidase activity. Predicted to be involved in asparagine metabolic process; glutamine metabolic process; and oxaloacetate metabolic process. Predicted to localize to cytoplasm. Is expressed in pronephric duct. Orthologous to human NIT2 (nitrilase family member 2).
Genome Resources: Alliance (1),  Gene:402904 (1),  Ensembl(GRCz11):ENSDARG00000017590 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2005 [eu995]
  6 figures (4 images) from Thisse et al., 2004 [IMAGE:7162355]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11457 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa38561 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nit2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nit2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process nitrogen compound metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nit2-201 (1)    Ensembl 1299
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nit2 No data available
    MARKER RELATIONSHIPS
    nit2 Contained in: [BAC] DKEY-66A8 (1) (order this)
    nit2 Encodes: [EST] eu995 (1), IMAGE:7162355 (1)
    [cDNA] MGC:109720 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205611 (1) 1324 nt
    Genomic GenBank:BX324166 (1) 215450 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1R818 (1) 284 aa
    Sequence Information (all 17)
    ORTHOLOGY for nit2 ( Chr: 6 )
    CITATIONS (26)